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战创伤及特殊作业环境相关急性肾损伤的防治
作者:蔡广研 陈香美 
单位:100853  北京 解放军总医院肾脏病科/全军肾脏病研究所/肾脏疾病国家重点实验室/国家慢性肾病临床医学研究中心(蔡广研、陈香美) 
关键词:战创伤 急性肾损伤 生物标志物 肾脏替代治疗 
分类号:R691.6
出版年,卷(期):页码:2019,44(7):546-549
摘要:

急性肾损伤(AKI)是由各种病因引起的肾功能快速下降,是战创伤及特殊作业环境下的常见危重症。战创伤及特殊作业环境相关AKI具有发病率、病死率高,存活患者远期预后差等特殊性。该文介绍了战创伤及特殊作业环境相关AKI的病因、发病机制及主要分类,阐述了AKI的早期诊断、救治现状及存在的问题。同时,针对AKI基础研究不断深入,以及新型诊断标志物及肾脏替代治疗设备研究日益活跃的现状,为了适应未来战创伤及特殊作业环境相关AKI的救治需求,该文提出了相应的防治策略,并对未来该领域的发展趋势进行了展望。

Acute kidney injury (AKI) is a rapid decline in renal function caused by various etiologies, and is a common critical disease in combat and special working environment. The combat injury and special working environment-related AKI have the characteristics of high incidence and mortality, and the long-term prognosis of survival patients is poor. The present paper introduces the etiology, pathogenesis and main classification of AKI related to combat injury and special working environment, and expounds the present situation of early diagnosis and treatment of AKI and the existing problems. At present, the basic research on AKI is deepening, and the application of new diagnostic markers and renal replacement therapy equipment are becoming more and more active. In order to meet the treatment needs of AKI related to combat injury and special working environment in the future, this paper puts forward the corresponding prevention and treatment strategies, and looks forward to the development trend in this field in the future.

基金项目:
国家重点研发计划课题(2018YFA0108803);北京市科技计划课题(D181100000118004)
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